Dichloromethane → 4-(1H-pyrrolo(2,3-b)pyridin-3-yl)piperidine

HRID 140627Notes

Reaction equation

HRID 140627 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][nH:16][c:17]3[n:18][cH:19][cH:20][cH:21][c:22]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:30][CH2:31][Cl:32].[F:23][C:24]([F:25])([F:26])[C:27]([OH:28])=[O:29]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][nH:16][c:17]3[n:18][cH:19][cH:20][cH:21][c:22]23)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 49758876tert-butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine-1-carboxylate

Product 1

HCID 55294774-(1H-pyrrolo(2,3-b)pyridin-3-yl)piperidine

Sources & evidence

ORD record
ord-6c2b446278804343bfc8112fbe5c6561
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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