HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[4-(4-Chloro-2-fluoro-phenoxy)-phenyl]-ethylamine → Pyrimidine-5-carboxylic acid-(1-{1-[4-(4-chloro-2-fluoro-phenoxy)-phenyl]-ethylcarbamoyl}-cyclopropyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[4-(4-Chloro-2-fluoro-phenoxy)-phenyl]-ethylamine | HCID 58487912 | — |
| Reactant | 1-[(Pyrimidine-5-carbonyl)-amino]cyclopropanecarboxylic acid | HCID 59496291 | — |
| Product | Pyrimidine-5-carboxylic acid-(1-{1-[4-(4-chloro-2-fluoro-phenoxy)-phenyl]-ethylcarbamoyl}-cyclopropyl)-amide | HCID 25232240 | 29% |
Reaction Steps
Analogously to Example (1e) the title compound was prepared from 1-[(pyrimidine-5-carbonyl)-amino]-cyclopropanecarboxylic acid and 1-[4-(4-chloro-2-fluoro-phenoxy)-phenyl]-ethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916589B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-13df96a26a9844fc88a9de8c373d225f |
| Source note | uspto-grants-2014_12 |