HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1406336Generated: October 31, 2026
Ammonia → 3-Fluoro-4-(4-methoxy-phenoxy)-benzylamine
https://huagongshe.com/reaction/1406336
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Fluoro-4-(4-methoxy-phenoxy)-benzaldehyde | HCID 28604102 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | 3-Fluoro-4-(4-methoxy-phenoxy)-benzylamine | HCID 28966254 | — |
Reaction Steps
73.9 mg (0.3 mmol) of 3-fluoro-4-(4-methoxy-phenoxy)-benzaldehyde are dissolved in 5 ml of methanolic ammonia, combined with Ra—Ni and shaken for about 9 hours at 35° C. and 3 bar H2 pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08916589B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-d8b5367d71c94ce6a4b191e15f18e3dc |
|---|
| Source note | uspto-grants-2014_12 |
|---|
