2-Chlorophenol → HCID 66790269, compound

Participants

Reaction Steps

156 mg (1 mmol) of 2,4-difluoracetophenone were dissolved in 5 ml DMSO, taken and combined with 200 mg (1.45 mmol) of K2CO3. 128 mg (1 mmol) of 2-chlorophenol were dissolved in 5 ml DMSO and added thereto and the mixture was stirred for 2 days at ambient temperature. The reaction mixture was filtered through basic Alox, washed with DMF and concentrated by rotary evaporation. The substance was purified by reversed-phase chromatography.

Provenance & Evidence