反应详情

温度

120 °C

A solution of 50 mg (0.40 mmol) of 4-fluorobenzaldehyde and 83.6 mg (0.40 mmol) of 4-bromo-2-chlorophenol in 2 mL DMSO was combined with 80 mg (0.58 mmol) of potassium carbonate and stirred overnight at 120° C. The reaction mixture was filtered through Alox B, washed with dichloromethane and evaporated down. The residue was purified by chromatography (reversed phase).

1. filtrationThe reaction mixture was filtered through Alox B
2. washwashed with dichloromethane
3. customevaporated down
4. customThe residue was purified by chromatography (reversed phase)