m-Chloroperbenzoic acid → HCID 58487916, compound

HRID 1406386Notes

Reaction equation

HRID 1406386 reaction equation
[CH3:1][O:2][C:3]1[CH:34]=[CH:33][C:6]([O:7][C:8]2[CH:32]=[CH:31][C:11]([CH2:12][NH:13][C:14]([C:16]3([NH:19][C:20]([C:22]4[CH:23]=[N:24][C:25]([S:28]([CH3:30])=[O:29])=[N:26][CH:27]=4)=[O:21])[CH2:18][CH2:17]3)=[O:15])=[CH:10][CH:9]=2)=[C:5]([C:35]([F:38])([F:37])[F:36])[CH:4]=1.ClC1C=CC=C(C(OO)=[O:47])C=1>>[CH3:1][O:2][C:3]1[CH:34]=[CH:33][C:6]([O:7][C:8]2[CH:9]=[CH:10][C:11]([CH2:12][NH:13][C:14]([C:16]3([NH:19][C:20]([C:22]4[CH:23]=[N:24][C:25]([S:28]([CH3:30])(=[O:47])=[O:29])=[N:26][CH:27]=4)=[O:21])[CH2:17][CH2:18]3)=[O:15])=[CH:31][CH:32]=2)=[C:5]([C:35]([F:36])([F:38])[F:37])[CH:4]=1

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 58487855HCID 58487855, compound

Product 1

HCID 58487916HCID 58487916, compound

Procedure

Half the crude product mixture from Example 148 was combined with a further 186 mg 3-chloroperbenzoic acid and stirred for two hours at ambient temperature. After the solution had been evaporated down the crude product thus obtained was purified by chromatography (reversed phase HPLC).

Workup

  1. customAfter the solution had been evaporated down the crude product
  2. customthus obtained
  3. customwas purified by chromatography (reversed phase HPLC)

Sources & evidence

ORD record
ord-a55ed5eb1bb9410f826b80ccdf2a8f98
Source dataset
uspto-grants-2014_12
Patent number
US08916589B2

Reaction notes

Loading…