HCID 35028755, compound → HCID 67232093, compound

HRID 1406446Notes

Reaction equation

HRID 1406446 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][C:9](=[O:20])[C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[C:12]([N+:17]([O-])=O)[CH:11]=2)[CH:3]=1>[Ni].C1COCC1>[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][C:9](=[O:20])[C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[C:12]([NH2:17])[CH:11]=2)[CH:3]=1

Participants

4

Reactant 1

HCID 35028755HCID 35028755, compound

Product 1

HCID 67232093HCID 67232093, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 14b from the product obtained in 116b by hydrogenation using Raney nickel in THF at 3.5 bar.

Workup

  1. customPrepared analogously to example 14b from the product

Sources & evidence

ORD record
ord-16c31adb07c3411da2f08d058281d316
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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