Diisopropylcarbodiimide → HCID 178497380, compound

HRID 1406447Notes

Reaction equation

HRID 1406447 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[NH2:12])[C:5]([O:7][CH3:8])=[O:6].[Cl:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[C:15]=1[N:21]=[C:22]=S.CC(C)N=C=NC(C)C>C(#N)C>[CH3:8][O:7][C:5]([C:4]1[CH:9]=[CH:10][C:11]2[NH:12][C:22]([NH:21][C:15]3[C:14]([Cl:13])=[CH:19][CH:18]=[CH:17][C:16]=3[Cl:20])=[N:1][C:2]=2[CH:3]=1)=[O:6]

Participants

5

Reactant 3

HCID 12734DiisopropylcarbodiimideHCID 1232391,3-Dichloro-2-isothiocyanatobenzeneHCID 1355243,5-Diamino-2-methylbenzoic acid

Product 1

HCID 178497380HCID 178497380, compoundYield 56%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared analogously to example 1c from methyl 3,4-diamino-benzoate and 2,6-dichloro-1-isothiocyanato-benzene with DIC in acetonitrile. Yield: 56%

Sources & evidence

ORD record
ord-fc888a4f2d8145d0adab4fb3ae685eff
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

Loading…