Neopentylamine → HCID 178446468, compound

HRID 1406464Notes

Reaction equation

HRID 1406464 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]1[NH:14][C:13]2[CH:15]=[CH:16][C:17]([C:19](O)=[O:20])=[CH:18][C:12]=2[N:11]=1.[CH3:22][C:23]([CH3:27])([CH3:26])[CH2:24][NH2:25].CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F>CN(C=O)C>[CH3:22][C:23]([CH3:27])([CH3:26])[CH2:24][NH:25][C:19]([C:17]1[CH:16]=[CH:15][C:13]2[NH:14][C:10]([NH:9][C:3]3[C:4]([Cl:8])=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])=[N:11][C:12]=2[CH:18]=1)=[O:20]

Participants

5

Reactant 3

HCID 79882NeopentylamineHCID 2733207O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 178524175HCID 178524175, compound

Product 1

HCID 178446468HCID 178446468, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to example 3c from 2-(2,6-dichloro-phenylamino)-1H-benzimidazole-5-carboxylic acid, 2,2-dimethyl-propylamine, TEA and TBTU in DMF.

Sources & evidence

ORD record
ord-820d130615334e9f923b207cb3d9dbf2
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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