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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1406474Generated: October 30, 2026

2-Fluoro-4-nitrobenzoic acid → 4-Amino-2-fluorobenzoic acid

https://huagongshe.com/reaction/1406474

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-nitrobenzoic acidHCID 302679—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
Product4-Amino-2-fluorobenzoic acidHCID 302680—

Reaction Steps

Prepared analogously to example 1b by hydrogenation of 2-fluoro-4-nitro-benzoic acid using palladium/charcoal 10% in THF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916599B2
Source datasetuspto-grants-2014_12
ORD IDord-8307f8d12c4e461696f600df3b4746f8
Source noteuspto-grants-2014_12