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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1406477Generated: October 31, 2026

Hydrochloric Acid → 4-Amino-2-fluoro-5-nitrobenzoic acid

https://huagongshe.com/reaction/1406477

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4-Acetamido-2-fluoro-5-nitrobenzoic acidHCID 67230302—
Solvent1,4-DioxaneHCID 31275—
Product4-Amino-2-fluoro-5-nitrobenzoic acidHCID 59785337—

Reaction Steps

Prepared analogously to example 145b from 4-acetylamino-2-fluoro-5-nitro-benzoic acid and half-conc. hydrochloric acid in dioxane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916599B2
Source datasetuspto-grants-2014_12
ORD IDord-3b58e9717b744d12acc4f82c63d1455c
Source noteuspto-grants-2014_12