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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1406478Generated: October 30, 2026

Thionyl Chloride → 4-Amino-5-nitro-2-fluoro-benzoyl chloride

https://huagongshe.com/reaction/1406478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant4-Amino-2-fluoro-5-nitrobenzoic acidHCID 59785337—
Solvent1,2-DichloroethaneHCID 11—
Product4-Amino-5-nitro-2-fluoro-benzoyl chlorideHCID 86660380—

Reaction Steps

Prepared analogously to example 53a from 4-amino-5-nitro-2-fluoro-benzoic acid and thionyl chloride in 1,2-dichloroethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916599B2
Source datasetuspto-grants-2014_12
ORD IDord-dce61302b2cc40dfb349ecacfd1c3a60
Source noteuspto-grants-2014_12