HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 4-amino-2-fluoro-5-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Amino-5-nitro-2-fluoro-benzoyl chloride | HCID 86660380 | — |
| Product | Ethyl 4-amino-2-fluoro-5-nitrobenzoate | HCID 59529828 | 89% |
Reaction Steps
A solution of the product obtained at 149e (1.4 g, 6.4 mmol) in 50 mL ethanol was heated to reflux for 2 h. The mixture was filtered and the filtrate concentrated i.vac. The residue is reacted without any further purification. Yield: 89%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916599B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-bb09c702cf3849beb02397cf6bbc8c08 |
| Source note | uspto-grants-2014_12 |