HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-amino-2-fluoro-5-nitrobenzoate → Ethyl 4,5-diamino-2-fluorobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-amino-2-fluoro-5-nitrobenzoate | HCID 59529828 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ethyl 4,5-diamino-2-fluorobenzoate | HCID 67230558 | — |
Reaction Steps
Prepared analogously to example 1b by hydrogenation of 4-amino-5-nitro-2-fluoro-benzoic acid ethyl ester using palladium/charcoal 10% in methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916599B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-8e42cc9d319c4f1e9ddf91216aa9a661 |
| Source note | uspto-grants-2014_12 |