HCID 60651014, compound → HCID 67232611, compound

HRID 1406492Notes

Reaction equation

HRID 1406492 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][C:5]([C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([Br:15])=[CH:11][N:10]=2)=[O:7])=[CH:4][C:3]=1[N+:18]([O-])=O>[Ni].C1COCC1>[NH2:18][C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][C:2]=1[NH2:1])[C:6]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([Br:15])=[CH:11][N:10]=1)=[O:7]

Participants

4

Reactant 1

HCID 60651014HCID 60651014, compound

Product 1

HCID 67232611HCID 67232611, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 14b by hydrogenation of 4-amino-N-(5-bromo-pyridin-2-yl)-3-nitro-benzamide using Raney nickel in THF.

Sources & evidence

ORD record
ord-956c9c0a6ced49a590b49d572ab5fcd7
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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