反应详情

温度

60 °C

40 mL liquid methylamine was added to a stirred mixture of N-(4-bromo-phenyl)-4-fluoro-3-nitro-benzamide (1.5 g, 4.4 mmol) in a pressure tube. The mixture was stirred for 20 h at 60° C. The mixture was cooled and concentrated i.vac. The residue was taken up in ethyl acetate, filtered with celite and silica gel and dried.

1. temperatureThe mixture was cooled
2. concentrationconcentrated i.vac
3. filtrationfiltered with celite and silica gel
4. customdried