Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 3651415 | HCID 3651415 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 7406921 | HCID 7406921 | — |
Reaction Steps
A mixture of N-(4-bromo-phenyl)-4-fluoro-3-nitro-benzamide (1.5 g, 4.4 mmol) and 40 mL liquid methyl amine was stirred for 20 h at 60° C. The mixture was cooled to −78° C., diluted with ethyl acetate and filtered with celite and silica gel. The filtrate was concentrated i.vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08916599B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-0a73107cc7f54b6b8d163ed303ace639 |
|---|
| Source note | uspto-grants-2014_12 |
|---|
