Cyclohexylamine → HCID 58562358, compound

HRID 1406511Notes

Reaction equation

HRID 1406511 reaction equation
[Br:1][C:2]1[C:7]2[N:8]([CH3:20])[C:9]([NH:11][C:12]3[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=3[Cl:19])=[N:10][C:6]=2[CH:5]=[C:4]([C:21]([OH:23])=O)[CH:3]=1.[CH:24]1([NH2:30])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1.CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F>CN(C=O)C>[CH:24]1([NH:30][C:21]([C:4]2[CH:3]=[C:2]([Br:1])[C:7]3[N:8]([CH3:20])[C:9]([NH:11][C:12]4[C:13]([Cl:19])=[CH:14][CH:15]=[CH:16][C:17]=4[Cl:18])=[N:10][C:6]=3[CH:5]=2)=[O:23])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

5

Reactant 3

HCID 7965CyclohexylamineHCID 2733207O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 86660390HCID 86660390, compound

Product 1

HCID 58562358HCID 58562358, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to example 3c from 7-bromo-2-(2,6-dichloro-phenylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid, cyclohexylamine, TBTU and TEA in DMF.

Sources & evidence

ORD record
ord-6b42b78500134a71a191ac25606f5342
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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