Dicyclohexylcarbodiimide → HCID 178521838, compound

HRID 1406516Notes

Reaction equation

HRID 1406516 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][C:17]=1[NH2:18])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][CH:9]=1)=[O:6].[Cl:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([N:26]=[C:27]=S)[C:21]=1[C:29]([F:32])([F:31])[F:30].C1CCC(N=C=NC2CCCCC2)CC1>CN(C=O)C>[Br:14][C:11]1[CH:10]=[CH:9][C:8]([NH:7][C:5]([C:4]2[CH:15]=[CH:16][C:17]3[NH:18][C:27]([NH:26][C:22]4[CH:23]=[CH:24][CH:25]=[C:20]([Cl:19])[C:21]=4[C:29]([F:32])([F:30])[F:31])=[N:1][C:2]=3[CH:3]=2)=[O:6])=[CH:13][CH:12]=1

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 85602456HCID 85602456, compoundHCID 86660393HCID 86660393, compound

Product 1

HCID 178521838HCID 178521838, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to example 106a from 3,4-diamino-N-(4-bromo-phenyl)-benzamide, 1-chloro-3-isothiocyanato-2-trifluoromethyl-benzene and DCC in DMF.

Sources & evidence

ORD record
ord-306fb4ccdbfc41799d9e4da3881cf93f
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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