HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 4-amino-2,3-difluoro-5-nitro-, methyl ester → Methyl 4,5-diamino-2,3-difluorobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 4-amino-2,3-difluoro-5-nitro-, methyl ester | HCID 2759749 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 4,5-diamino-2,3-difluorobenzoate | HCID 86651263 | — |
Reaction Steps
Prepared analogously to example 1b by hydrogenation of methyl 4-amino-2,3-difluoro-5-nitrobenzoate using palladium/charcoal 10% in methanol and dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916599B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-53c3acf550eb48bca230c7a5964b64e2 |
| Source note | uspto-grants-2014_12 |