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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1406523Generated: October 31, 2026

Ethanol → Ethyl 2,4-difluoro-5-nitrobenzoate

https://huagongshe.com/reaction/1406523

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant2,4-Difluoro-5-nitrobenzoyl chlorideHCID 18314497—
SolventTetrahydrofuranHCID 8028—
ProductEthyl 2,4-difluoro-5-nitrobenzoateHCID 22330120—

Reaction Steps

Prepared analogously to example 156a from 2,4-difluoro-5-nitro-benzoyl chloride (5.0 g, 22.6 mmol), ethanol and TEA in THF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916599B2
Source datasetuspto-grants-2014_12
ORD IDord-600e91d12571459f8d69dd80a55d4666
Source noteuspto-grants-2014_12