Tetrahydrofuran → tert-butyl (2RS,4SR,5SR)-1-{2-[3-(3-(ethoxycarbonyl)phenyl)ureido]acetyl}-5-(2-fluorophenyl)-4-(morpholinocarbonyl)pyrrolidine-2-carboxylate
Reaction equation
[N:32](=[C:33]=[O:34])[c:35]1[cH:36][c:37]([C:38](=[O:39])[O:40][CH2:41][CH3:42])[cH:43][cH:44][cH:45]1.[NH2:1][CH2:2][C:3](=[O:4])[N:5]1[CH:6]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:7][CH:8]([C:17](=[O:18])[N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[CH:9]1[c:10]1[c:11]([F:16])[cH:12][cH:13][cH:14][cH:15]1.[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[NH:1]([CH2:2][C:3](=[O:4])[N:5]1[CH:6]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:7][CH:8]([C:17](=[O:18])[N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[CH:9]1[c:10]1[c:11]([F:16])[cH:12][cH:13][cH:14][cH:15]1)[C:33]([NH:32][c:35]1[cH:36][c:37]([C:38](=[O:39])[O:40][CH2:41][CH3:42])[cH:43][cH:44][cH:45]1)=[O:34]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f82fc67016ae4d28994ac49120f6efb8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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