Dichloromethane → 2-amino-4,4,4-trifluoro-N-[1-(4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]butanamide
Reaction equation
[CH2:57]1[CH2:58][CH2:59][NH:60][CH2:61][CH2:62]1.[Cl:63][CH2:64][Cl:65].[F:1][C:2]([CH2:3][CH:4]([C:5](=[O:6])[NH:7][C:8]([CH2:9][c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)([c:16]1[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]1)[c:23]1[cH:24][c:25]([F:36])[cH:26][c:27]([O:29][C:30]([CH:31]([F:32])[F:33])([F:34])[F:35])[cH:28]1)[NH:37][C:38](=[O:39])[O:40][CH2:41][CH:42]1[c:43]2[cH:44][cH:45][cH:46][cH:47][c:48]2-[c:49]2[c:50]1[cH:51][cH:52][cH:53][cH:54]2)([F:55])[F:56]>>[F:1][C:2]([CH2:3][CH:4]([C:5](=[O:6])[NH:7][C:8]([CH2:9][c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)([c:16]1[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]1)[c:23]1[cH:24][c:25]([F:36])[cH:26][c:27]([O:29][C:30]([CH:31]([F:32])[F:33])([F:34])[F:35])[cH:28]1)[NH2:37])([F:55])[F:56]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0698fb897e094d5689840a69c6331bb0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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