HRID1408178

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12315

N-Methyl-N-propylamine

C4H11N

结构：CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCN3CCOCC3)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1

HCID56952022

未命名化合物

PRODUCTS

生成物

结构：CCCN(C)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCN3CCOCC3)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1

HCID66588229

未命名化合物

PROCEDURE

实验过程

This compound was prepared according to the procedure described for the synthesis of N1-(4-(diethylamino)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)-N3-methyl-N3-(2-morpholinoethyl)isophthalamide 25, using N-methylpropan-1-amine in place of diethylamine. MS (ES, m/z): 717.3 [M+H]+.

WORKUP

后处理

customThis compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ce070154d4d74fbf9a5461a18e3748c2
来源数据集: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08916569B2
来源说明: uspto-grants-2014_12

反应 SMILES

[CH2:1]([N:3]([CH2:51][CH3:52])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:30])[C:12]2[CH:29]=[CH:28][CH:27]=[C:14]([C:15]([N:17]([CH3:26])[CH2:18][CH2:19][N:20]3[CH2:25][CH2:24][O:23][CH2:22][CH2:21]3)=[O:16])[CH:13]=2)=[C:6]([C:31]2[CH:36]=[C:35]([C:37](=[O:50])[NH:38][CH2:39][C:40]3[CH:45]=[CH:44][CH:43]=[C:42]([C:46]([F:49])([F:48])[F:47])[CH:41]=3)[CH:34]=[CH:33][N:32]=2)[CH:5]=1)C.[CH3:53]NCCC>>[CH3:26][N:17]([CH2:18][CH2:19][N:20]1[CH2:21][CH2:22][O:23][CH2:24][CH2:25]1)[C:15](=[O:16])[C:14]1[CH:27]=[CH:28][CH:29]=[C:12]([C:11]([NH:10][C:7]2[CH:8]=[CH:9][C:4]([N:3]([CH3:1])[CH2:51][CH2:52][CH3:53])=[CH:5][C:6]=2[C:31]2[CH:36]=[C:35]([C:37](=[O:50])[NH:38][CH2:39][C:40]3[CH:45]=[CH:44][CH:43]=[C:42]([C:46]([F:49])([F:47])[F:48])[CH:41]=3)[CH:34]=[CH:33][N:32]=2)=[O:30])[CH:13]=1