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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1408178Generated: October 30, 2026

N-Methylpropylamine → N1-methyl-N3-(4-(methyl(propyl)amino)-2-(4-((3-(trifluoromethyl)benzyl) carbamoyl)pyridin-2-yl)phenyl)-N-(2-morpholinoethyl)isophthalamide

https://huagongshe.com/reaction/1408178

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylpropylamineHCID 12315—
ReactantN1-(4-(diethylamino)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)-N3-methyl-N3-(2-morpholinoethyl)isophthalamideHCID 56952022—
ProductN1-methyl-N3-(4-(methyl(propyl)amino)-2-(4-((3-(trifluoromethyl)benzyl) carbamoyl)pyridin-2-yl)phenyl)-N-(2-morpholinoethyl)isophthalamideHCID 66588229—

Reaction Steps

This compound was prepared according to the procedure described for the synthesis of N1-(4-(diethylamino)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)-N3-methyl-N3-(2-morpholinoethyl)isophthalamide 25, using N-methylpropan-1-amine in place of diethylamine. MS (ES, m/z): 717.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916569B2
Source datasetuspto-grants-2014_12
ORD IDord-ce070154d4d74fbf9a5461a18e3748c2
Source noteuspto-grants-2014_12