Hydrochloric Acid → 1-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-3-fluoro-pyrrolidine
Reaction equation
[Br:9][CH2:10][CH2:11][CH2:12][O:13][Si:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[CH3:20].[CH3:27][C:28]#[N:29].[ClH:1].[ClH:2].[F:3][CH:4]1[CH2:5][NH:6][CH2:7][CH2:8]1.[K+:21].[K+:22].[O-:23][C:24]([O-:25])=[O:26].[OH2:30]>>[F:3][CH:4]1[CH2:5][N:6]([CH2:10][CH2:11][CH2:12][O:13][Si:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:7][CH2:8]1Participants
8
Sources & evidence
- ORD record
- ord-7c12394a8b4746e19817628f3784dfe4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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