Ethyl Acetate → Methyl 1-(2-amino-5-formylphenyl)piperidine-4-carboxylate

HRID 140833Notes

Reaction equation

HRID 140833 reaction equation
[CH3:25][CH2:26][O:27][C:28]([CH3:29])=[O:30].[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6]([N+:19]([O-:20])=[O:21])[c:7]([N:9]2[CH2:10][CH2:11][CH:12]([C:15](=[O:16])[O:17][CH3:18])[CH2:13][CH2:14]2)[cH:8]1.[H:22][H:23].[Pd:24]>>[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6]([NH2:19])[c:7]([N:9]2[CH2:10][CH2:11][CH:12]([C:15](=[O:16])[O:17][CH3:18])[CH2:13][CH2:14]2)[cH:8]1

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 23938PalladiumHCID 59803194Methyl 1-(5-formyl-2-nitrophenyl)piperidine-4-carboxylateHCID 178418361HCID 178418361, compound

Product 1

HCID 59803196Methyl 1-(2-amino-5-formylphenyl)piperidine-4-carboxylate

Sources & evidence

ORD record
ord-3b03b8340ea2432a8b50c6e3a44c2c37
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…