HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazine → HCID 46202650, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazine | HCID 224967 | — |
| Reactant | 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine | HCID 2756555 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 46202650 | HCID 46202650 | 69% |
Reaction Steps
Following the general procedure A, 4,4′-(6-chloro-1,3,5-triazine-2,4-diyl)dimorpholine was coupled with 2-aminopyridine-5-boronic acid pinacol ester with the reaction time of 15 h. Chromatography (methylene chloride/methanol 97:3) gave 69% of the title compound as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921361B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-a7928f8ea5994e2a9ce65ab086874272 |
| Source note | uspto-grants-2014_12 |