Piconol → HCID 58508055, compound

HRID 1408456Notes

Reaction equation

HRID 1408456 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([Cl:8])[N:5]=[C:4](NCCN2CCCCC2)[N:3]=1.[N:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[CH2:24][OH:25]>>[Cl:8][C:6]1[N:7]=[C:2]([Cl:1])[N:3]=[C:4]([O:25][CH2:24][C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][N:18]=2)[N:5]=1

Participants

3

Reactant 2

HCID 11474PiconolHCID 58507984HCID 58507984, compound

Product 1

HCID 58508055HCID 58508055, compound

Procedure

Following the general procedure A-2, 4,6-dichloro-N-(2-(piperidin-1-yl)ethyl)-1,3,5-triazin-2-amine was coupled with 2-pyridinemethanol with reaction time of 3 h. Purification by column chromatography gave the title compound.

Workup

  1. customPurification by column chromatography

Sources & evidence

ORD record
ord-69a53b8a33094f5cbd5d8275d8fb105d
Source dataset
uspto-grants-2014_12
Patent number
US08921361B2

Reaction notes

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