HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 58507693, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 58507731 | HCID 58507731 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | HCID 58507693 | HCID 58507693 | — |
Reaction Steps
tert-butyl 2-(2-(3-(tert-butyldimethylsilyloxy)phenyl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)ethylcarbamate (10.0 mg, 1.0 eq.) was solved in 3 ml of TFA:DCM (1:1). The reaction mixture was stirred at room temperature for 2 h. The silica column chromatography (DCM:MeOH/95:5) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921361B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-27cb6ccf2ac34710901134b6955a57ef |
| Source note | uspto-grants-2014_12 |