Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1408823Generated: November 2, 2026

Water → HCID 178481310, compound

https://huagongshe.com/reaction/1408823

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantCesium carbonateHCID 10796—
Reactant3-Pyridinylboronic acidHCID 2734378—
ReactantHCID 178481309HCID 178481309—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178481310HCID 178481310—

Reaction Steps

To a solution of 6-bromo-2′-imino-1′-methyl-2-phenyl-2′,3′-dihydro-1′H-spiro[chroman-4,4′-pyrimidin]-6′(5′H)-one TFA salt (12 mg, 0.023 mmol) and pyridin-3-ylboronic acid (9 mg, 0.070 mmol) in 1,4-dioxane (3 mL) charged in a 10-mL microwave test tube is added Cs2CO3 (63 mg, 0.195 mmol) and H2O (0.5 mL), followed by

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921359B2
Source datasetuspto-grants-2014_12
ORD IDord-8eb7afd876e64f98bbd1c568abc28d91
Source noteuspto-grants-2014_12