Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclopentylamine | HCID 2906 | — |
| Reactant | 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine | HCID 46835522 | — |
| Product | HCID 58896840 | HCID 58896840 | — |
Reaction Steps
To 4-bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine (D) was added cyclopentylamine (0.5 mL) in a sealed tube. The mixture was heated to 110° C. for 24-48 h. The mixture was concentrated. Preparative HPLC provided 5-chloro-N-cyclopentyl-1H-pyrrolo[2,3-b]pyridin-4-amine (127)(7.4 mg) as the TFA salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08921376B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-ad17d807e86648f0bb6d4aae90cacb00 |
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| Source note | uspto-grants-2014_12 |
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