Tetrahydrofuran → HCID 58441736, compound

HRID 140914Notes

Reaction equation

HRID 140914 reaction equation
[C:22](=[O:23])([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[N:29]1[CH2:30][CH2:31][C:32](=[O:35])[CH2:33][CH2:34]1.[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[Cl:1][c:2]1[n:3][c:4]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][s:10]2.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[Cl:1][c:2]1[n:3][c:4]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([C:32]1([OH:35])[CH2:31][CH2:30][N:29]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:34][CH2:33]1)[s:10]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 202849712-Chloro-4-(morpholin-4-yl)thieno(3,2-d)pyrimidineHCID 178418339Butyllithium

Product 1

HCID 58441736HCID 58441736, compound

Sources & evidence

ORD record
ord-7698844fd4e14baa97dff1f72c227d05
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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