HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 136377095, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 136377096 | HCID 136377096 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 136377095 | HCID 136377095 | 53% |
Reaction Steps
The compound was prepared according to the same procedure as in Example 21 using 2-(2-bromo-5-trifluoromethyl-benzyl)-5-hydroxy-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid methyl ester (0.080 g; 0.197 mmol) and 2M methylamine solution in THF (1 ml). This provided the title product as an off-white solid (0.043 g; 53%). LCMS: m/z=427 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921388B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-8d6edd145af34fe2858946a075ac467f |
| Source note | uspto-grants-2014_12 |