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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409585Generated: November 1, 2026

Methylamine → HCID 136377095, compound

https://huagongshe.com/reaction/1409585

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantHCID 136377096HCID 136377096—
SolventTetrahydrofuranHCID 8028—
ProductHCID 136377095HCID 13637709553%

Reaction Steps

The compound was prepared according to the same procedure as in Example 21 using 2-(2-bromo-5-trifluoromethyl-benzyl)-5-hydroxy-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid methyl ester (0.080 g; 0.197 mmol) and 2M methylamine solution in THF (1 ml). This provided the title product as an off-white solid (0.043 g; 53%). LCMS: m/z=427 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921388B2
Source datasetuspto-grants-2014_12
ORD IDord-8d6edd145af34fe2858946a075ac467f
Source noteuspto-grants-2014_12