HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Methylimidazole → 2-(2-Methyl-imidazol-1-yl)-pyrimidine-5-carboxylic acid cyclopropyl-piperidin-4-yl-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Methylimidazole | HCID 12749 | — |
| Edukt | 4-[(2-Chloro-pyrimidine-5-carbonyl)-cyclopropyl-amino]-piperidine-1-carboxylic acid tert-butyl ester | HCID 86686152 | — |
| Produkt | 2-(2-Methyl-imidazol-1-yl)-pyrimidine-5-carboxylic acid cyclopropyl-piperidin-4-yl-amide | HCID 71093756 | — |
Reaktionsschritte
The title compound is prepared from 4-[(2-chloro-pyrimidine-5-carbonyl)-cyclopropyl-amino]-piperidine-1-carboxylic acid tert-butyl ester and 2-methyl-1H-imidazole following procedures analogous to those described in Intermediate 16 and Intermediate 17. LC (method 10): tR=0.56 min; Mass spectrum (ESI+): m/z=327 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08921398B2 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-7109d1fa1e604a01b2083c72a5951018 |
| Quellennotiz | uspto-grants-2014_12 |