HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Pyridin-4-yl)pyrimidine-5-carboxylic acid → 2-Pyridin-4-yl-pyrimidine-5-carboxylic acid cyclopropyl-[1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Pyridin-4-yl)pyrimidine-5-carboxylic acid | HCID 22710213 | — |
| Reactant | N-cyclopropyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)piperidin-4-amine | HCID 68289604 | — |
| Product | 2-Pyridin-4-yl-pyrimidine-5-carboxylic acid cyclopropyl-[1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-amide | HCID 71112008 | — |
Reaction Steps
The title compound is prepared from cyclopropyl-[1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-amine and 2-pyridin-4-yl-pyrimidine-5-carboxylic acid following a procedure analogous to that described in Example 1. LC (method 2): tR=1.76 min; Mass spectrum (ESI+): m/z=468 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921398B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-4d2e31dc00f844ffbbb3f982b4dbdf31 |
| Source note | uspto-grants-2014_12 |