HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-ethylpyrimidine → 2-Imidazol-1-yl-pyrimidine-5-carboxylic acid cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| Reactant | N-cyclopropyl-2-(1H-imidazol-1-yl)-N-(piperidin-4-yl)pyrimidine-5-carboxamide | HCID 71093743 | — |
| Product | 2-Imidazol-1-yl-pyrimidine-5-carboxylic acid cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-amide | HCID 86686168 | — |
Reaction Steps
The title compound is prepared from 2-imidazol-1-yl-pyrimidine-5-carboxylic acid cyclopropyl-piperidin-4-yl-amide and 2-chloro-5-ethylpyrimidine following a procedure analogous to that described in Example 3. LC (method 10): tR=1.40 min; Mass spectrum (ESI+): m/z=419 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921398B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-c2014ecdb078459386968baa97b83526 |
| Source note | uspto-grants-2014_12 |