Methyl 3,3-dimethoxypropionate → HCID 178495579, compound

Participants

Reaction Steps

The title compound, white solid (71 mg, 64%), MS (ISP) m/z=443.4 [(M+H)+], mp 148° C., was prepared in accordance with the general method of example 46 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and methyl 3,3-dimethoxy-propanoate.

Provenance & Evidence