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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409922Generated: October 31, 2026

(1,1'-Biphenyl)-4-carboxylic acid → HCID 178523639, compound

https://huagongshe.com/reaction/1409922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178523639HCID 178523639—

Reaction Steps

The title compound, yellow solid (119 mg, 94%), MS (ISP) m/z=507.3 [(M+H)+], mp 235° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and biphenyl-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-fb54f8ed45f1436d9515b1202847c0f0
Source noteuspto-grants-2014_12