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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409934Generated: October 26, 2026

4-Tert-butylcyclohexane-1-carboxylic acid → HCID 178440970, compound

https://huagongshe.com/reaction/1409934

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Tert-butylcyclohexane-1-carboxylic acidHCID 136759—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178440970HCID 178440970—

Reaction Steps

The title compound, off-white solid (77 mg, 63%), MS (ISP) m/z=493.4 [(M+H)+], mp 199° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 4-tert-butyl-cyclohexanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-1d4c56f2d3444edf910c8d448c57b156
Source noteuspto-grants-2014_12