Ammonium Chloride → HCID 59529864, compound

HRID 1410241Notes

Reaction equation

HRID 1410241 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:25])[C:10]2[CH:15]=[CH:14][C:13]([NH:16][CH2:17][CH2:18][N:19]([CH3:21])[CH3:20])=[C:12]([N+:22]([O-])=O)[CH:11]=2)=[CH:4][CH:3]=1.[NH4+].[Cl-]>[Fe].CCO>[NH2:22][C:12]1[CH:11]=[C:10]([CH:15]=[CH:14][C:13]=1[NH:16][CH2:17][CH2:18][N:19]([CH3:21])[CH3:20])[C:9]([NH:8][C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=1)=[O:25]

Participants

5

Reactant 2

HCID 25517Ammonium ChlorideHCID 59529894HCID 59529894, compound

Product 1

HCID 59529864HCID 59529864, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 702EthanolSolvent

Procedure

The sub-title compound was prepared in accordance with the procedure in Example 2, step (b) using N-(4-bromophenyl)-4-(2-(dimethylamino)ethylamino)-3-nitrobenzamide (560 mg; 1.38 mmol), Fe (384 mg; 6.88 mmol), NH4Cl (aq, sat, 10 mL) and EtOH (10 mL).

Sources & evidence

ORD record
ord-f658b5f425ae4614864e4a004fa8ef28
Source dataset
uspto-grants-2014_12
Patent number
US08921405B2

Reaction notes

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