Azetidine hydrochloride → HCID 90449660, compound

Participants

Reaction Steps

The captioned compound was obtained in the form of a white solid by performing the same reactions and/or treatments as those in Examples 29 and 85, with the exceptions that the ethyl 4-(1′-(methylcarbamoyl)-1-((5-methylpyrazin-2-yl)carbamoyl)spiro[indoline-3,3′-pyrrolidin]-5-yl)butanoate obtained in Example 420 was used instead of 2-((2-(1′-acetyl-5-bromospiro[indoline-3,3′-pyrrolidin]-1-ylcarboxamido)thiazol-5-yl)thio)acetate, and that azetidine hydrochloride was used instead of dimethylamine hydrochloride.

Provenance & Evidence