Dichloromethane → 2-Methyl-4-pyridin-3-yl-2,7-diaza-spiro[4.5]decan-1-one

HRID 141148Notes

Reaction equation

HRID 141148 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10]2([CH:11]([c:17]3[cH:18][n:19][cH:20][cH:21][cH:22]3)[CH2:12][N:13]([CH3:16])[C:14]2=[O:15])[CH2:23][CH2:24][CH2:25]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32]>>[NH:8]1[CH2:9][C:10]2([CH:11]([c:17]3[cH:18][n:19][cH:20][cH:21][cH:22]3)[CH2:12][N:13]([CH3:16])[C:14]2=[O:15])[CH2:23][CH2:24][CH2:25]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 71060602HCID 71060602, compound

Product 1

HCID 710602182-Methyl-4-pyridin-3-yl-2,7-diaza-spiro[4.5]decan-1-one

Sources & evidence

ORD record
ord-445a8bd1e17340ad88410ee6c70fbe67
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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