Hydrochloric Acid → HCID 12878936, compound

Participants

Reaction Steps

The ethyl 2-fluoro-fluoren-9-one-1-carboxylate is mixed with 500 ml of NaOH 6N and refluxed for 2 hours. After cooling, the mixture is diluted with twice its volume of water and acidified with concentrated HCl. The yellow precipitate that forms is filtered and washed with water. The melting point of the pure product isolated from column chromatography on silica gel (eluant: CHCl3 /CH3CO2C2H5 3/1) is: 209.210° C.

Provenance & Evidence