Morpholine → HCID 20549212, compound

HRID 1413088Notes

Reaction equation

HRID 1413088 reaction equation
[CH2:1]([C:3]1([C:11](Cl)=[O:12])[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[CH3:10])[CH3:2].[NH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>CCOCC>[CH2:1]([C:3]1([C:11]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[O:12])[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[CH3:10])[CH3:2]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 20549168HCID 20549168, compound

Product 1

HCID 20549212HCID 20549212, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

1-Ethyl-2-methylcycloheptanecarbonyl chloride (1.5 g, 0.007 mole) in ether (10 ml.) was added slowly to a solution of morpholine (0.02 mole) in ether (10 ml.). The mixture was washed with dilute hydrochloric acid, dilute sodium bicarbonate and then with water. The ether layer was dried and distilled to give N-(1-ethyl-2-methylcycloheptanecarbonyl) morpholine bp. 145°-7°/0.35 mm.

Workup

  1. washThe mixture was washed with dilute hydrochloric acid, dilute sodium bicarbonate
  2. dry with materialThe ether layer was dried
  3. distillationdistilled

Sources & evidence

ORD record
ord-c4f5f83320274cd5b5f3e8fa830c25a1
Source dataset
uspto-grants-1981_02
Patent number
US04248859

Reaction notes

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