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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1413263Generated: October 31, 2026

Nitric Acid → 2-(1,1-Dimethylethyl)-4-methyl-1H-imidazole-5-carboxaldehyde

https://huagongshe.com/reaction/1413263

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitric AcidHCID 944—
ReactantHCID 12493281HCID 12493281—
Product2-(1,1-Dimethylethyl)-4-methyl-1H-imidazole-5-carboxaldehydeHCID 12493285—

Reaction Steps

A 19.76 gm. portion of 2-tert-butyl-5-methyl-4-imidazolemethanol and 16.5 ml. of concentrated HNO3 are reacted as described in Example 25 giving the desired product, m.p. 196°-198° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE030511
Source datasetuspto-grants-1981_02
ORD IDord-7bd7d981330b4d09b79531b636f5013d
Source noteuspto-grants-1981_02