Methanethiol → HCID 12493298, compound

HRID 1413278Notes

Reaction equation

HRID 1413278 reaction equation
C[S:2][C:3](=S)[NH:4][N:5]=[CH:6][C:7]1[N:8]=[CH:9][NH:10][CH:11]=1.CS>C1(OC2C=CC=CC=2)C=CC=CC=1>[CH:6]1[C:7]2[N:8]([CH:9]=[N:10][CH:11]=2)[C:3](=[S:2])[NH:4][N:5]=1

Participants

4

Reactant 2

HCID 878MethanethiolHCID 178504099HCID 178504099, compound

Product 1

HCID 12493298HCID 12493298, compound

Reagents, catalysts & solvents 1

HCID 7583Diphenyl EtherSolvent

Procedure

A suspension of 164.5 gm. of 3-(4-imidazolylmethylene)dithiocarbazic acid methyl ester in 1.2 liters of diphenyl ether is heated and stirred at 175° C. until the methylmercaptan evolution subsides (20 minutes). The precipitate obtained on cooling to room temperature is collected and washed with petroleum ether, then acetone. The precipitate is then slurried with 1.2 liters of boiling methanol and filtered while hot to give the desired product, m.p. 271°-273° C.

Workup

  1. additionA suspension of 164.5 gm
  2. customThe precipitate obtained
  3. customis collected
  4. washwashed with petroleum ether
  5. filtrationfiltered while hot

Sources & evidence

ORD record
ord-6a0f82022018475a80f0c43a497aa902
Source dataset
uspto-grants-1981_02
Patent number
USRE030511

Reaction notes

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