Benzene → HCID 178474722, compound

HRID 1413319Notes

Reaction equation

HRID 1413319 reaction equation
[C:1]([CH:5]1[C:10](=[O:11])[CH2:9][CH:8]([C:12]([S:15][C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)([CH3:14])[CH3:13])[CH2:7][C:6]1=[O:23])(=O)[CH2:2][CH3:3].[CH2:24]([O:27][NH2:28])[CH:25]=C.C1C=CC=CC=1>C(O)C>[CH2:24]([O:27][NH:28][C:1](=[C:5]1[C:10](=[O:11])[CH2:9][CH:8]([C:12]([S:15][C:16]2[CH:17]=[CH:18][C:19]([CH3:22])=[CH:20][CH:21]=2)([CH3:14])[CH3:13])[CH2:7][C:6]1=[O:23])[CH2:2][CH3:3])[CH3:25]

Participants

5

Reactant 3

HCID 241BenzeneHCID 420841O-AllylhydroxylamineHCID 20291505HCID 20291505, compound

Product 1

HCID 178474722HCID 178474722, compoundYield 68.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.3 g of 2-propionyl-5-[1-(p-tolylthio)isopropyl]cyclohexane-1,3-dione was allowed to react with 0.3 g of allyloxyamine at room temperature for 15 hours in the mixture of 10 ml of benzene and 3 ml of ethanol. After completion of the reaction, the resulting reaction solution was treated as in Example 1 to obtain 1 g of the desired compound.

Workup

  1. customAfter completion of the reaction
  2. customthe resulting reaction solution
  3. additionwas treated as in Example 1

Sources & evidence

ORD record
ord-9e7b91a6e4f645edaa38669c88e490a8
Source dataset
uspto-grants-1981_02
Patent number
US04249937

Reaction notes

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