Benzaldehyde → HCID 13521819, compound

HRID 1413322Notes

Reaction equation

HRID 1413322 reaction equation
[CH2:1]([S:3][CH2:4][CH:5]([OH:8])[CH2:6][NH2:7])[CH3:2].[CH:9](=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.O>C1C=CC=CC=1>[C:10]1([CH:9]2[NH:7][CH2:6][CH:5]([CH2:4][S:3][CH2:1][CH3:2])[O:8]2)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

5

Reactant 3

HCID 240BenzaldehydeHCID 962WaterHCID 13521817HCID 13521817, compound

Product 1

HCID 13521819HCID 13521819, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Thirteen and five tenths (13.5) grams of 2-hydroxy-3-aminopropyl ethyl sulfide and 10.6 grams of benzaldehyde were combined in 100 milliliters of benzene and refluxed under a modified Dean-Stark apparatus until about 2 milliliters of water had been azetropically removed. The mixture was cooled to room temperature and the volume adjusted to 89.2 milliliters (4 milliliters=1 gram). Aliquots of this mixture were used in subsequent reactions.

Workup

  1. customhad been azetropically removed

Sources & evidence

ORD record
ord-a7a9c903dbbf4c8ea6b4967f8055f4ba
Source dataset
uspto-grants-1981_02
Patent number
US04249931

Reaction notes

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