Hydrochloric Acid → 2-(cyclopropylamino)acetic acid hydrochloride(WX191407S1)

Participants

Reaction Steps

Ethyl cyclopropylaminoacetate was stirred in a mixture of concentrated hydrochloric acid and water until the reaction had subsided. The mixture was then heated to reflux for 2 hours. The resulting solution was evaporated to give a white solid which was triturated with acetone and recrystallised from methanol/ethyl acetate to give cyclopropylaminoacetic acid hydrochloride of melting point 189°-191° C. (decomposition).

Provenance & Evidence